VWD Tax Attorney 11-1-13 Vincent W. Davis & Associates Law Offices California

What is von Willebrand Disease?

Von Willebrand's disease (VWD) is a genetic disorder caused by Willebrand's missing or defective factor (VWF), a protein that coagulates. VWF binds factor VIII, a key protein for clotting, and platelets in the walls of the blood vessels, helping to form a platelet plug during the coagulation process. The condition is named after Erik von Willebrand, a Finnish physician who first described it in the 1920s.

VWD is the most common bleeding disorder affecting up to 1 percent of the population in the United States. It is carried on chromosome 12 and happens in men and women alike.

People with VWD experience frequent nosebleeds, easy bruising, and excessive bleeding during and after invasive procedures, such as dental extractions and surgery. Women often experience severe menstrual bleeding (heavy menstrual periods that last longer than the average), and post-birth hemorrhaging.

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